Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives

Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives

Synthesis of some biologically active benzothiazolotriazine derivatives by microwave irradiation is reported. 2-Amino-6-substituted benzothiazoles 1 on treatment with benzaldehyde in anhydrous ethanol afforded 2-benzylidenoimino-6-substitutedbenzothiazoles 2 which underwent cyclisation with ammonium...

Full description

Bibliographic Details
Main Authors: Prashant Kriplani, Pawan Swarnkar, Rinku Maheshwari, K. G. Ojha
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2006/486723
id doaj-d58212df65dc47b4baadfd9462570d32
record_format Article
spelling doaj-d58212df65dc47b4baadfd9462570d322020-11-24T23:00:33ZengHindawi LimitedE-Journal of Chemistry0973-49452090-98102006-01-013430731210.1155/2006/486723Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine DerivativesPrashant Kriplani0Pawan Swarnkar1Rinku Maheshwari2K. G. Ojha3Department of Pure and Applied Chemistry, M. D. S. University, Ajmer-305 009, IndiaDepartment of Pure and Applied Chemistry, M. D. S. University, Ajmer-305 009, IndiaDepartment of Pure and Applied Chemistry, M. D. S. University, Ajmer-305 009, IndiaDepartment of Pure and Applied Chemistry, M. D. S. University, Ajmer-305 009, IndiaSynthesis of some biologically active benzothiazolotriazine derivatives by microwave irradiation is reported. 2-Amino-6-substituted benzothiazoles 1 on treatment with benzaldehyde in anhydrous ethanol afforded 2-benzylidenoimino-6-substitutedbenzothiazoles 2 which underwent cyclisation with ammoniumthiocyanate in dioxane to give 2-phenyl benzothiazolo [3,2-α]-s-triazine-4-[3H] thiones 3.These both steps were carried out in microwave. Compound 3 with benzoyl chloride in anhydrous pyridine gave 2-phenyl-3-(benzoyl) benzothiazolo [3,2-α]-s-triazine-4-thiones 4 in good yields. The structure of all these compounds have been supported by their elemental analysis and their spectral data. All synthesized compounds were tested for their antibacterial activity using standard drug.http://dx.doi.org/10.1155/2006/486723
collection DOAJ
language English
format Article
sources DOAJ
author Prashant Kriplani
Pawan Swarnkar
Rinku Maheshwari
K. G. Ojha
spellingShingle Prashant Kriplani
Pawan Swarnkar
Rinku Maheshwari
K. G. Ojha
Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives
E-Journal of Chemistry
author_facet Prashant Kriplani
Pawan Swarnkar
Rinku Maheshwari
K. G. Ojha
author_sort Prashant Kriplani
title Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives
title_short Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives
title_full Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives
title_fullStr Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives
title_full_unstemmed Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives
title_sort microwave assisted synthesis of some biologically active benzothiazolotriazine derivatives
publisher Hindawi Limited
series E-Journal of Chemistry
issn 0973-4945
2090-9810
publishDate 2006-01-01
description Synthesis of some biologically active benzothiazolotriazine derivatives by microwave irradiation is reported. 2-Amino-6-substituted benzothiazoles 1 on treatment with benzaldehyde in anhydrous ethanol afforded 2-benzylidenoimino-6-substitutedbenzothiazoles 2 which underwent cyclisation with ammoniumthiocyanate in dioxane to give 2-phenyl benzothiazolo [3,2-α]-s-triazine-4-[3H] thiones 3.These both steps were carried out in microwave. Compound 3 with benzoyl chloride in anhydrous pyridine gave 2-phenyl-3-(benzoyl) benzothiazolo [3,2-α]-s-triazine-4-thiones 4 in good yields. The structure of all these compounds have been supported by their elemental analysis and their spectral data. All synthesized compounds were tested for their antibacterial activity using standard drug.
url http://dx.doi.org/10.1155/2006/486723
work_keys_str_mv AT prashantkriplani microwaveassistedsynthesisofsomebiologicallyactivebenzothiazolotriazinederivatives
AT pawanswarnkar microwaveassistedsynthesisofsomebiologicallyactivebenzothiazolotriazinederivatives
AT rinkumaheshwari microwaveassistedsynthesisofsomebiologicallyactivebenzothiazolotriazinederivatives
AT kgojha microwaveassistedsynthesisofsomebiologicallyactivebenzothiazolotriazinederivatives
_version_ 1725642039085760512

Similar Items