Serum levels of proteins involved in amyloid‐β clearance are related to cognitive decline and neuroimaging changes in mild cognitive impairment

Serum levels of proteins involved in amyloid‐β clearance are related to cognitive decline and neuroimaging changes in mild cognitive impairment

Abstract Introduction Amyloid‐β (Aβ) clearance is important for damage prevention in Alzheimer's disease. We investigated the utility of Aβ clearance proteins as biomarkers for mild cognitive impairment (MCI). Methods Serum apolipoprotein (apo) A‐I, compliment protein C3 (C3), transthyretin, an...

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Bibliographic Details
Main Authors: Shan Liu, Hideaki Suzuki, Hitomi Ito, Tatsumi Korenaga, Hiroyasu Akatsu, Kohji Meno, Kazuhiko Uchida
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Alzheimer's disease
Biomarker
Complement protein
Microglia
Neuroinflammation
Online Access:https://doi.org/10.1016/j.dadm.2018.11.003

Internet

https://doi.org/10.1016/j.dadm.2018.11.003

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