The effects of locomotion on bone marrow mesenchymal stem cell fate: insight into mechanical regulation and bone formation

The effects of locomotion on bone marrow mesenchymal stem cell fate: insight into mechanical regulation and bone formation

Abstract Bone marrow mesenchymal stem cells (BMSCs) refer to a heterogeneous population of cells with the capacity for self-renewal. BMSCs have multi-directional differentiation potential and can differentiate into chondrocytes, osteoblasts, and adipocytes under specific microenvironment or mechanic...

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Bibliographic Details
Main Authors: Yuanxiu Sun, Yu Yuan, Wei Wu, Le Lei, Lingli Zhang
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cell & Bioscience
Subjects:
Exercise
Mechanoresponse
Signaling pathway
Differentiation
Online Access:https://doi.org/10.1186/s13578-021-00601-9

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