A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans

A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans

How multicellular organisms respond to and are impacted by severe hypothermic stress is largely unknown. From C. elegans screens for mutants abnormally responding to cold-warming stimuli, we identify a molecular genetic pathway comprising ISY-1, a conserved uncharacterized protein, and ZIP-10, a bZI...

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Bibliographic Details
Main Authors: Wei Jiang, Yuehua Wei, Yong Long, Arthur Owen, Bingying Wang, Xuebing Wu, Shuo Luo, Yongjun Dang, Dengke K Ma
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-04-01
Series:eLife
Subjects:
hypothermia
bZIP transcription factor
ISY1 or ISY-1
ZIP-10
C. elegans screen
forward genetics
Online Access:https://elifesciences.org/articles/35037

Internet

https://elifesciences.org/articles/35037

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