Schwann cell-like differentiated adipose stem cells promote neurite outgrowth via secreted exosomes and RNA transfer

Schwann cell-like differentiated adipose stem cells promote neurite outgrowth via secreted exosomes and RNA transfer

Abstract Background Adipose derived stem cells can be stimulated to produce a growth factor rich secretome which enhances axon regeneration. In this study we investigated the importance of exosomes, extracellular vesicles released by many different cell types, including stem cells and endogenous ner...

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Bibliographic Details
Main Authors: Rosanna C Ching, Mikael Wiberg, Paul J Kingham
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Stem Cell Research & Therapy
Subjects:
Exosomes
Extracellular vesicles
Peripheral nerves
Regeneration
Schwann cells
Stem cells
Online Access:http://link.springer.com/article/10.1186/s13287-018-1017-8

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