Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior

Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior

Increased tonic activity of locus coeruleus noradrenergic (LC-NE) neurons induces anxiety-like and aversive behavior. While some information is known about the afferent circuitry that endogenously drives this neural activity and behavior, the downstream receptors and anatomical projections that medi...

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Bibliographic Details
Main Authors: Jordan G McCall, Edward R Siuda, Dionnet L Bhatti, Lamley A Lawson, Zoe A McElligott, Garret D Stuber, Michael R Bruchas
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-07-01
Series:eLife
Subjects:
locus coeruleus
basolateral amygdala
norepinephrine
anxiety
optogenetics
β-adrenergic receptor
Online Access:https://elifesciences.org/articles/18247

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