TNF-α inhibitor reduces drug-resistance to anti-PD-1: A mathematical model.

Drug resistance is a primary obstacle in cancer treatment. In many patients who at first respond well to treatment, relapse occurs later on. Various mechanisms have been explored to explain drug resistance in specific cancers and for specific drugs. In this paper, we consider resistance to anti-PD-1...

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Bibliographic Details
Main Authors: Xiulan Lai, Wenrui Hao, Avner Friedman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231499