MicroRNA 876-5p modulates EV-A71 replication through downregulation of host antiviral factors
Abstract Background Human enterovirus 71 (EV-A71) is a non-enveloped virus that has a single stranded positive sense RNA genome. In a previous study, we showed that miR-876-5p upregulation was observed in the serum of patients with severe EV-A71 infection. Micro-876-5p (miR-876-5p) is a circulating...
Main Authors: | Peng Xu, Hwa Xu, Hsu Sheng Cheng, Han-Hsiang Chan, Robert Y. L. Wang |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-02-01
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Series: | Virology Journal |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12985-020-1284-8 |
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