In vivo studies on antibiotic combination for the treatment of carbapenem-resistant Gram-negative bacteria: a systematic review and meta-analysis protocol

Objective There is poor evidence to determine the superiority of combination regimens versus monotherapy against infections due to carbapenem-resistant (CR) Gram-negative bacteria. In vivo models can simulate the pathophysiology of infections in humans and assess antibiotic efficacy. We aim to inves...

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Main Authors: Sally Ellis, Evelina Tacconelli, Laura Piddock, Luigia Scudeller, Elda Righi, Elena Carrara, Maurizio Sanguinetti, Margherita Chiamenti, Kamilia Abdelraouf, Thomas Lodise, Alessia Savoldi, Dario Menghin, Gloria Pellizzari, Francois Franceschi, Chiara Rebuffi
Format: Article
Language:English
Published: BMJ Publishing Group 2020-11-01
Series:BMJ Open Science
Online Access:https://openscience.bmj.com/content/4/1/e100055.full