Beyond T Cells: Understanding the Role of PD-1/PD-L1 in Tumor-Associated Macrophages

Beyond T Cells: Understanding the Role of PD-1/PD-L1 in Tumor-Associated Macrophages

Programmed cell death protein 1 (PD-1) and its ligand PD-L1 have attracted wide attention from researchers in the field of immunotherapy. PD-1/PD-L1 have been shown to exist in many types of cells in addition to T lymphocytes, and studies have accordingly extended from their suppressive effect on T...

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Bibliographic Details
Main Authors: Di Lu, Zhen Ni, Xiguang Liu, Siyang Feng, Xiaoying Dong, Xiaoshun Shi, Jianxue Zhai, Shijie Mai, Jianjun Jiang, Zhizhi Wang, Hua Wu, Kaican Cai
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2019/1919082

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