Prognostic significance of cyclin D1 protein expression and gene amplification in invasive breast carcinoma.

Prognostic significance of cyclin D1 protein expression and gene amplification in invasive breast carcinoma.

The oncogenic capacity of cyclin D1 has long been established in breast cancer. CCND1 amplification has been identified in a subset of patients with poor prognosis, but there are conflicting data regarding the predictive value of cyclin D1 protein overexpression. This study was designed to analyze t...

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Bibliographic Details
Main Authors: Angela B Ortiz, Diego Garcia, Yolanda Vicente, Magda Palka, Carmen Bellas, Paloma Martin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5687747?pdf=render

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