Fosl1 overexpression directly activates trophoblast-specific gene expression programs in embryonic stem cells

During early development in placental mammals, proper trophoblast lineage development is essential for implantation and placentation. Defects in this lineage can cause early pregnancy failures and other pregnancy disorders. However, transcription factors controlling trophoblast development remain po...

Full description

Bibliographic Details
Main Authors: Bum-Kyu Lee, Nadima Uprety, Yu Jin Jang, Scott K. Tucker, Catherine Rhee, Lucy LeBlanc, Samuel Beck, Jonghwan Kim
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117302635