Fluoxetine Induced Suicidal Erythrocyte Death

Fluoxetine Induced Suicidal Erythrocyte Death

The antidepressant fluoxetine inhibits ceramide producing acid sphingomyelinase. Ceramide is in turn known to trigger eryptosis the suicidal death of erythrocytes characterized by cell shrinkage and exposure of phosphatidylserine at the erythrocyte surface. Ceramide is effective through sensitizing...

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Bibliographic Details
Main Authors: Florian Lang, Majed Abed, Ahmad Almilaji, Rosi Bissinger, Sigrid Enkel, Kashif Jilani
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Toxins
Subjects:
phosphatidylserine
fluoxetine
calcium
cell volume
eryptosis
Online Access:http://www.mdpi.com/2072-6651/5/7/1230

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