Solid-Phase Parallel Synthesis of Drug-Like Artificial 2<em>H</em>-Benzopyran Libraries

Solid-Phase Parallel Synthesis of Drug-Like Artificial 2<em>H</em>-Benzopyran Libraries

This review covers the construction of drug-like 2<em>H</em>-benzopyrans and related libraries using solid-phase parallel synthesis. In this context, the preparation of substituted benzopyrans such as mono-, di- and trisubstituted benzopyran derivatives and additional rin...

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Bibliographic Details
Main Authors: Young-Dae Gong, Taeho Lee
Format: Article
Language:English
Published: MDPI AG 2012-05-01
Series:Molecules
Subjects:
combinatorial chemistry
solid-phase synthesis
chemical library
drug-like molecules
2<em>H</em>-benzopyran
Online Access:http://www.mdpi.com/1420-3049/17/5/5467
Description
Summary:This review covers the construction of drug-like 2<em>H</em>-benzopyrans and related libraries using solid-phase parallel synthesis. In this context, the preparation of substituted benzopyrans such as mono-, di- and trisubstituted benzopyran derivatives and additional ring-fused benzopyrans such as benzopyranoisoxazoles, benzopyranopyrazoles, six-membered ring-fused benzopyrans, and polycyclic benzopyrans are highlighted.
ISSN:1420-3049

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