Differential, phosphorylation dependent trafficking of AQP2 in LLC-PK1 cells.

Differential, phosphorylation dependent trafficking of AQP2 in LLC-PK1 cells.

The kidney maintains water homeostasis by modulating aquaporin 2 (AQP2) on the plasma membrane of collecting duct principal cells in response to vasopressin (VP). VP mediated phosphorylation of AQP2 at serine 256 is critical for this effect. However, the role of phosphorylation of other serine resid...

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Bibliographic Details
Main Authors: William L Rice, Yan Zhang, Ying Chen, Toshiyuki Matsuzaki, Dennis Brown, Hua A Jenny Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3293519?pdf=render

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