Effects of Protein Kinase A on the Phosphorylation Status and Transverse Stiffness of Cardiac Myofibrils

Effects of Protein Kinase A on the Phosphorylation Status and Transverse Stiffness of Cardiac Myofibrils

Stimulation of β-adrenergic receptors in cardiac myocytes activates cyclic AMP– dependent protein kinase A (PKA). PKA-mediated phosphorylation of myofibrils decreases their longitudinal stiffness, but its effect on transverse stiffness is not fully understood. We thus examined the effects of PKA tre...

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Bibliographic Details
Main Authors: Yoshiki Ohnuki, Takenori Yamada, Yasumasa Mototani, Daisuke Umeki, Kouichi Shiozawa, Takayuki Fujita, Yasutake Saeki, Satoshi Okumura
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319302518

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http://www.sciencedirect.com/science/article/pii/S1347861319302518

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