Resveratrol protects human nucleus pulposus cells from degeneration by blocking IL-6/JAK/STAT3 pathway

Resveratrol protects human nucleus pulposus cells from degeneration by blocking IL-6/JAK/STAT3 pathway

Abstract Background Nucleus pulposus cells’ (NPCs’) degeneration is mainly responsible for the intervertebral disc degeneration (IDD), which is closely related to inflammatory response. Among the major proinflammatory factors that are related to NPCs’ degeneration, interleukin-6 (IL-6) and its downs...

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Bibliographic Details
Main Authors:	Cenhao Wu, Jun Ge, Ming Yang, Qi Yan, Yingjie Wang, Hao Yu, Huilin Yang, Jun Zou
Format:	Article
Language:	English
Published:	BMC 2021-07-01
Series:	European Journal of Medical Research
Subjects:	Resveratrol Nucleus pulposus cells IL-6/JAK/STAT3 pathway Intervertebral disc degeneration Proinflammatory factors Positive feedback
Online Access:	https://doi.org/10.1186/s40001-021-00555-1

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