An Exploratory Study of Daprodustat in Erythropoietin-Hyporesponsive Subjects

Introduction: Hyporesponsiveness to recombinant human erythropoietin (rhEPO) is a major problem affecting some patients with chronic kidney disease (CKD), predominantly those on hemodialysis (HD). Daprodustat (GSK1278863) is a hypoxia-inducible factor prolyl hydroxylase inhibitor that is being inves...

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Bibliographic Details
Main Authors: Borut Cizman, Andy P. Sykes, Gitanjali Paul, Steven Zeig, Alexander R. Cobitz
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Kidney International Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024918300408