Control of Microbial Opsin Expression in Stem Cell Derived Cones for Improved Outcomes in Cell Therapy

Control of Microbial Opsin Expression in Stem Cell Derived Cones for Improved Outcomes in Cell Therapy

Human-induced pluripotent stem cell (hiPSC) derived organoids have become increasingly used systems allowing 3D-modeling of human organ development, and disease. They are also a reliable source of cells for transplantation in cell therapy and an excellent model to validate gene therapies. To make fu...

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Bibliographic Details
Main Authors: Marcela Garita-Hernandez, Antoine Chaffiol, Laure Guibbal, Fiona Routet, Hanen Khabou, Luisa Riancho, Lyes Toualbi, Serge Picaud, José-Alain Sahel, Olivier Goureau, Jens Duebel, Deniz Dalkara
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
human induced pluripotent stem cell
human retinal organoid
cones
optogenetics
vision restoration
cell therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.648210/full

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