A drug delivery strategy: binding enkephalin to asialoglycoprotein receptor by enzymatic galactosylation.

A drug delivery strategy: binding enkephalin to asialoglycoprotein receptor by enzymatic galactosylation.

Glycosylation of biopharmaceuticals can mediate cell specific delivery by targeting carbohydrate receptors. Additionally, glycosylation can improve the physico-chemical (drug-like) properties of peptide based drug candidates. The main purpose of this study was to examine if glycosylation of the pept...

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Bibliographic Details
Main Authors: Michelle P Christie, Pavla Simerská, Freda E-C Jen, Waleed M Hussein, Mohamad F M Rawi, Lauren E Hartley-Tassell, Christopher J Day, Michael P Jennings, Istvan Toth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3988166?pdf=render

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http://europepmc.org/articles/PMC3988166?pdf=render

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