Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo

Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo

Uptake of cholesterol from peripheral cells by nascent small HDL circulating in plasma is necessary to prevent atherosclerosis. This process, termed reverse cholesterol transport, produces larger cholesterol-rich HDL that transfers its cholesterol to the liver facilitating excretion. Most HDL in pla...

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Bibliographic Details
Main Authors: Frank M. Sacks, Lawrence L. Rudel, Adam Conner, Hassibullah Akeefe, Gerhard Kostner, Talal Baki, George Rothblat, Margarita de la Llera-Moya, Bela Asztalos, Timothy Perlman, Chunyu Zheng, Petar Alaupovic, Jo-Ann B. Maltais, H. Bryan Brewer
Format: Article
Language:English
Published: Elsevier 2009-05-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein A-I
kinetics
lipoproteins
nonhuman primates
ABCA1
SRB1
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520308427

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