Normal cells repel WWOX-negative or -dysfunctional cancer cells via WWOX cell surface epitope 286-299

Yu-An Chen et al characterize the role of cell surface epitopes of the tumor suppressor protein WWOX in cell–cell recognition. The find that cells expressing functional WWOX, repel cancer cells which express dysfunctional WWOX or lack this protein, in a manner mediated by WWOX epitope 286-299.

Bibliographic Details
Main Authors:	Yu-An Chen, Yong-Da Sie, Tsung-Yun Liu, Hsiang-Ling Kuo, Pei-Yi Chou, Yu-Jie Chen, Kuan-Ting Lee, Pin-Jun Chen, Shur-Tzu Chen, Nan-Shan Chang
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-06-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-021-02271-2

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spelling	doaj-d4f330c1830c430db0064e8e0e79db702021-06-20T11:28:10ZengNature Publishing GroupCommunications Biology2399-36422021-06-014111910.1038/s42003-021-02271-2Normal cells repel WWOX-negative or -dysfunctional cancer cells via WWOX cell surface epitope 286-299Yu-An Chen0Yong-Da Sie1Tsung-Yun Liu2Hsiang-Ling Kuo3Pei-Yi Chou4Yu-Jie Chen5Kuan-Ting Lee6Pin-Jun Chen7Shur-Tzu Chen8Nan-Shan Chang9Institute of Molecular Medicine, National Cheng Kung UniversityInstitute of Molecular Medicine, National Cheng Kung UniversityInstitute of Molecular Medicine, National Cheng Kung UniversityInstitute of Molecular Medicine, National Cheng Kung UniversityInstitute of Molecular Medicine, National Cheng Kung UniversityInstitute of Molecular Medicine, National Cheng Kung UniversityInstitute of Molecular Medicine, National Cheng Kung UniversityInstitute of Molecular Medicine, National Cheng Kung UniversityDepartment of Cell Biology and Anatomy, National Cheng Kung UniversityInstitute of Molecular Medicine, National Cheng Kung UniversityYu-An Chen et al characterize the role of cell surface epitopes of the tumor suppressor protein WWOX in cell–cell recognition. The find that cells expressing functional WWOX, repel cancer cells which express dysfunctional WWOX or lack this protein, in a manner mediated by WWOX epitope 286-299.https://doi.org/10.1038/s42003-021-02271-2
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Yu-An Chen Yong-Da Sie Tsung-Yun Liu Hsiang-Ling Kuo Pei-Yi Chou Yu-Jie Chen Kuan-Ting Lee Pin-Jun Chen Shur-Tzu Chen Nan-Shan Chang
spellingShingle	Yu-An Chen Yong-Da Sie Tsung-Yun Liu Hsiang-Ling Kuo Pei-Yi Chou Yu-Jie Chen Kuan-Ting Lee Pin-Jun Chen Shur-Tzu Chen Nan-Shan Chang Normal cells repel WWOX-negative or -dysfunctional cancer cells via WWOX cell surface epitope 286-299 Communications Biology
author_facet	Yu-An Chen Yong-Da Sie Tsung-Yun Liu Hsiang-Ling Kuo Pei-Yi Chou Yu-Jie Chen Kuan-Ting Lee Pin-Jun Chen Shur-Tzu Chen Nan-Shan Chang
author_sort	Yu-An Chen
title	Normal cells repel WWOX-negative or -dysfunctional cancer cells via WWOX cell surface epitope 286-299
title_short	Normal cells repel WWOX-negative or -dysfunctional cancer cells via WWOX cell surface epitope 286-299
title_full	Normal cells repel WWOX-negative or -dysfunctional cancer cells via WWOX cell surface epitope 286-299
title_fullStr	Normal cells repel WWOX-negative or -dysfunctional cancer cells via WWOX cell surface epitope 286-299
title_full_unstemmed	Normal cells repel WWOX-negative or -dysfunctional cancer cells via WWOX cell surface epitope 286-299
title_sort	normal cells repel wwox-negative or -dysfunctional cancer cells via wwox cell surface epitope 286-299
publisher	Nature Publishing Group
series	Communications Biology
issn	2399-3642
publishDate	2021-06-01
description	Yu-An Chen et al characterize the role of cell surface epitopes of the tumor suppressor protein WWOX in cell–cell recognition. The find that cells expressing functional WWOX, repel cancer cells which express dysfunctional WWOX or lack this protein, in a manner mediated by WWOX epitope 286-299.
url	https://doi.org/10.1038/s42003-021-02271-2
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Normal cells repel WWOX-negative or -dysfunctional cancer cells via WWOX cell surface epitope 286-299

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