Sequence features of <it>HLA-DRB1 </it>locus define putative basis for gene conversion and point mutations

<p>Abstract</p> <p>Background</p> <p>HLA/MHC class II molecules show high degree of polymorphism in the human population. The individual polymorphic motifs have been suggested to be propagated and mixed by transfer of genetic material (recombination, gene conversion) be...

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Bibliographic Details
Main Authors: von Salomé Jenny, Kukkonen Jyrki P
Format: Article
Language:English
Published: BMC 2008-05-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/228