Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway

Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway

Abstract Background Epithelial–mesenchymal transition (EMT) promotes migration, invasion, and metastasis of hepatocellular carcinoma (HCC) cells. The molecular mechanisms behind EMT and metastasis in HCC remain unclear. Methods Microarray analysis was used to identify lncRNAs expression during polar...

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Bibliographic Details
Main Authors: Hong-Lin Luo, Tao Luo, Jun-Jie Liu, Fei-Xiang Wu, Tao Bai, Chao Ou, Jie Chen, Le-Qun Li, Jian-Hong Zhong
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Cancer Cell International
Subjects:
Hepatocellular carcinoma
Long non-coding RNAs
Cancer migration
Epithelial–mesenchymal transition
Metastasis
Online Access:https://doi.org/10.1186/s12935-021-02133-1

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