Evaluating the efficacy of a structure-derived amino acid substitution matrix in detecting protein homologs by BLAST and PSI-BLAST
Nalin CW GoonesekereDepartment of Chemistry and Biochemistry, University of Northern iowa, Cedar Falls, IA, USAAbstract: The large numbers of protein sequences generated by whole genome sequencing projects require rapid and accurate methods of annotation. The detection of homology through computatio...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2009-06-01
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| Series: | Advances and Applications in Bioinformatics and Chemistry |
| Online Access: | http://www.dovepress.com/evaluating-the-efficacy-of-a-structure-derived-amino-acid-substitution-a3236 |