Embracing Mechanobiology in Next Generation Organ-On-A-Chip Models of Bone Metastasis
Bone metastasis in breast cancer is associated with high mortality. Biomechanical cues presented by the extracellular matrix play a vital role in driving cancer metastasis. The lack of in vitro models that recapitulate the mechanical aspects of the in vivo microenvironment hinders the development of...
Main Authors: | Ellen E. Slay, Fiona C. Meldrum, Virginia Pensabene, Mahetab H. Amer |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-09-01
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Series: | Frontiers in Medical Technology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmedt.2021.722501/full |
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