Phage-induced expression of CRISPR-associated proteins is revealed by shotgun proteomics in Streptococcus thermophilus.

The CRISPR/Cas system, comprised of clustered regularly interspaced short palindromic repeats along with their associated (Cas) proteins, protects bacteria and archaea from viral predation and invading nucleic acids. While the mechanism of action for this acquired immunity is currently under investi...

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Bibliographic Details
Main Authors: Jacque C Young, Brian D Dill, Chongle Pan, Robert L Hettich, Jillian F Banfield, Manesh Shah, Christophe Fremaux, Philippe Horvath, Rodolphe Barrangou, Nathan C Verberkmoes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3364186?pdf=render