A review on antibiotic resistance: Origin and mechanisms of bacterial resistance as biological phenomenon
Antimicrobial resistance is a natural biological phenomenon in their struggle for existence and represents a major health care issue, associated with high mortality and morbidity. The first cases of mass emergence of resistant strains were observed in the middle of the 20th century, and sin...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Serbian Genetics Society
2018-01-01
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| Series: | Genetika |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0534-0012/2018/0534-00121803123P.pdf |
| Summary: | Antimicrobial resistance is a natural biological phenomenon in their struggle
for existence and represents a major health care issue, associated with high
mortality and morbidity. The first cases of mass emergence of resistant
strains were observed in the middle of the 20th century, and since then
cases of resistance have been reported all over the world, and in the last
two decades even more frequently are reported multiple bacterial resistance.
Factors that contribute to the development of bacteria resistance are abuse
in the use of antibacterial agents, in humans or livestock, and releases of
antibacterial agents into the environment. Moreover, the development of new
effective antibiotics is decreasing, contrary to increasing the overall
effort for the synthesis of new ones. Identification and reporting of
bacterial resistance, as well as monitoring of the use of antibiotics in the
outpatient and inpatient setting, today is the obligation of all countries.
[Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 175011] |
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| ISSN: | 0534-0012 1820-6069 |