The role of sortilin in the “Glut4 Pathway”.
Sorting receptor, sortilin, is highly expressed in metabolically active tissues, such as brain, liver, skeletal muscle, and fat. Specifically in adipocytes, sortilin plays an important role in the “Glut4 pathway” by sorting the insulin-responsive glucose transporter, Glut4, in early endosomes and tr...
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Taylor & Francis Group
2018-01-01
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| Series: | Communicative & Integrative Biology |
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| Online Access: | http://dx.doi.org/10.1080/19420889.2017.1393592 |
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doaj-d4c7d9b005824b71a7d2b304325d558e2021-02-02T00:13:09ZengTaylor & Francis GroupCommunicative & Integrative Biology1942-08892018-01-0111110.1080/19420889.2017.13935921393592The role of sortilin in the “Glut4 Pathway”.Konstantin V. Kandror0Boston University School of MedicineSorting receptor, sortilin, is highly expressed in metabolically active tissues, such as brain, liver, skeletal muscle, and fat. Specifically in adipocytes, sortilin plays an important role in the “Glut4 pathway” by sorting the insulin-responsive glucose transporter, Glut4, in early endosomes and trans-Golgi network and re-routing the transporter from degradation to the recycling pathway.http://dx.doi.org/10.1080/19420889.2017.1393592GGAglucose uptakeGlut4retromersortilin |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Konstantin V. Kandror |
| spellingShingle |
Konstantin V. Kandror The role of sortilin in the “Glut4 Pathway”. Communicative & Integrative Biology GGA glucose uptake Glut4 retromer sortilin |
| author_facet |
Konstantin V. Kandror |
| author_sort |
Konstantin V. Kandror |
| title |
The role of sortilin in the “Glut4 Pathway”. |
| title_short |
The role of sortilin in the “Glut4 Pathway”. |
| title_full |
The role of sortilin in the “Glut4 Pathway”. |
| title_fullStr |
The role of sortilin in the “Glut4 Pathway”. |
| title_full_unstemmed |
The role of sortilin in the “Glut4 Pathway”. |
| title_sort |
role of sortilin in the “glut4 pathway”. |
| publisher |
Taylor & Francis Group |
| series |
Communicative & Integrative Biology |
| issn |
1942-0889 |
| publishDate |
2018-01-01 |
| description |
Sorting receptor, sortilin, is highly expressed in metabolically active tissues, such as brain, liver, skeletal muscle, and fat. Specifically in adipocytes, sortilin plays an important role in the “Glut4 pathway” by sorting the insulin-responsive glucose transporter, Glut4, in early endosomes and trans-Golgi network and re-routing the transporter from degradation to the recycling pathway. |
| topic |
GGA glucose uptake Glut4 retromer sortilin |
| url |
http://dx.doi.org/10.1080/19420889.2017.1393592 |
| work_keys_str_mv |
AT konstantinvkandror theroleofsortilinintheglut4pathway AT konstantinvkandror roleofsortilinintheglut4pathway |
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1724314325528608768 |