The fitness cost and benefit of phase‐separated protein deposits
Abstract Phase separation of soluble proteins into insoluble deposits is associated with numerous diseases. However, protein deposits can also function as membrane‐less compartments for many cellular processes. What are the fitness costs and benefits of forming such deposits in different conditions?...
Main Authors: | Natalia Sanchez de Groot, Marc Torrent Burgas, Charles NJ Ravarani, Ala Trusina, Salvador Ventura, M Madan Babu |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-04-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.15252/msb.20178075 |
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