CRISPR base editing and prime editing: DSB and template-free editing systems for bacteria and plants

CRISPR base editing and prime editing: DSB and template-free editing systems for bacteria and plants

CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats-CRISPR associated) has been extensively exploited as a genetic tool for genome editing. The RNA guided Cas nucleases generate DNA double-strand break (DSB), triggering cellular repair systems mainly Non-homologous end-joining (NHE...

Full description

Bibliographic Details
Main Authors:	Abdullah, Zhengzheng Jiang, Xulin Hong, Shun Zhang, Ruilian Yao, Yi Xiao
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2020-12-01
Series:	Synthetic and Systems Biotechnology
Subjects:	CRISPR Base editing Prime editing Cytosine base editor Adenine base editor
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405805X20300624

Similar Items

Development of a Simple and Quick Method to Assess Base Editing in Human Cells
by: Xiujuan Lv, et al.
Published: (2020-06-01)

CRISPR/Cas9-deaminase enables robust base editing in Rhodobacter sphaeroides 2.4.1
by: Yufeng Luo, et al.
Published: (2020-04-01)

Precise A•T to G•C base editing in the zebrafish genome
by: Wei Qin, et al.
Published: (2018-11-01)

CRISPR-mediated base editing in mice using cytosine deaminase base editor 4
by: Salah Adlat, et al.
Published: (2021-07-01)

Developing high-efficiency base editors by combining optimized synergistic core components with new types of nuclear localization signal peptide
by: Feipeng Wang, et al.
Published: (2020-06-01)

Advances in Genome Editing With CRISPR Systems and Transformation Technologies for Plant DNA Manipulation
by: Satya Swathi Nadakuduti, et al.
Published: (2021-01-01)

Highly efficient CRISPR-SaKKH tools for plant multiplex cytosine base editing
by: Chengwei Zhang, et al.
Published: (2020-06-01)

Designing sgRNAs for CRISPR-BEST base editing applications with CRISPy-web 2.0
by: Kai Blin, et al.
Published: (2020-06-01)

CRISPR-Cas9 DNA Base-Editing and Prime-Editing
by: Ariel Kantor, et al.
Published: (2020-08-01)

Delivery Approaches for Therapeutic Genome Editing and Challenges
by: Ilayda Ates, et al.
Published: (2020-09-01)

Predicting base editing outcomes using position-specific sequence determinants
by: Allen, F., et al.
Published: (2022)

Modeling Non-Alcoholic Fatty Liver Disease (NAFLD) Using “Good-Fit” Genome-Editing Tools
by: Uijin Kim, et al.
Published: (2020-12-01)

CRISPR-based genome editing technology and its applications in oil crops
by: Jianjie He, et al.
Published: (2021-07-01)

Increasing Cytosine Base Editing Scope and Efficiency With Engineered Cas9-PmCDA1 Fusions and the Modified sgRNA in Rice
by: Ying Wu, et al.
Published: (2019-04-01)

HDAC inhibitors improve CRISPR-Cas9 mediated prime editing and base editing
by: Hu, Y., et al.
Published: (2022)

Genome Editing in Rice: Recent Advances, Challenges, and Future Implications
by: Rukmini Mishra, et al.
Published: (2018-09-01)

Engineered extracellular vesicles as versatile ribonucleoprotein delivery vehicles for efficient and safe CRISPR genome editing
by: Xingang Yao, et al.
Published: (2021-03-01)

CRISPR-Based Genome Editing Tools: Insights into Technological Breakthroughs and Future Challenges
by: Muntazir Mushtaq, et al.
Published: (2021-05-01)

Editor’s Note On This Milestone Edition
by: Gert Roodt
Published: (2003-11-01)

Editorial: Mutation-Specific Gene Editing for Blood Disorders
by: Carsten Werner Lederer, et al.
Published: (2021-09-01)

CRISPR/Cas9 or prime editing? – It depends on…
by: Schenke Dirk
Published: (2020-12-01)

Formalisation of edit operations for structure editors
by: Holmquist, Johan
Published: (2005)

Base Editing: The Ever Expanding Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Tool Kit for Precise Genome Editing in Plants
by: Mahmuda Binte Monsur, et al.
Published: (2020-04-01)

Development of Plant Prime-Editing Systems for Precise Genome Editing
by: Rongfang Xu, et al.
Published: (2020-05-01)

Genome Editing Strategies Towards Enhancement of Rice Disease Resistance
by: Rukmini Mishra, et al.
Published: (2021-03-01)

Web-based design and analysis tools for CRISPR base editing
by: Gue-Ho Hwang, et al.
Published: (2018-12-01)

Development of genome editing technology of mitochondrial DNA in Saccharomyces cerevisiae
by: Amai, Takamitsu
Published: (2021)

Genome Engineering in Plant Using an Efficient CRISPR-xCas9 Toolset With an Expanded PAM Compatibility
by: Chengwei Zhang, et al.
Published: (2020-12-01)

Using Gene Editing Approaches to Fine-Tune the Immune System
by: Kristina Pavlovic, et al.
Published: (2020-09-01)

Efficient Generation and Correction of Mutations in Human iPS Cells Utilizing mRNAs of CRISPR Base Editors and Prime Editors
by: Duran Sürün, et al.
Published: (2020-05-01)

Various Aspects of a Gene Editing System—CRISPR–Cas9
by: Edyta Janik, et al.
Published: (2020-12-01)

Precise base editing for the in vivo study of developmental signaling and human pathologies in zebrafish
by: Marion Rosello, et al.
Published: (2021-02-01)

Therapeutic Editing of the <i>TP53</i> Gene: Is CRISPR/Cas9 an Option?
by: Regina Mirgayazova, et al.
Published: (2020-06-01)

Genome Editing Tools in Plants
by: Tapan Kumar Mohanta, et al.
Published: (2017-12-01)

Lentiviral Vectors for Delivery of Gene-Editing Systems Based on CRISPR/Cas: Current State and Perspectives
by: Wendy Dong, et al.
Published: (2021-07-01)

An optimized base editor with efficient C-to-T base editing in zebrafish
by: Yu Zhao, et al.
Published: (2020-12-01)

Tablet computers for the dissemination of digital scholarly editions
by: Aodhán Kelly
Published: (2015-09-01)

Prime Editing: Genome Editing for Rare Genetic Diseases Without Double-Strand Breaks or Donor DNA
by: Ianis G. Matsoukas, et al.
Published: (2020-06-01)

Comparison of cytosine base editors and development of the BEable-GPS database for targeting pathogenic SNVs
by: Ying Wang, et al.
Published: (2019-10-01)

The Analysis of the Results of Acceptability on the Translation Results in the Unedited Version and Edited Version in the Novel “After You”
by: Irma Fitriana Azti, et al.
Published: (2019-09-01)