Monte Carlo-based dose calculation for 32 P patch source for superficial brachytherapy applications

Skin cancer treatment involving 32 P source is an easy, less expensive method of treatment limited to small and superficial lesions of approximately 1 mm deep. Bhabha Atomic Research Centre (BARC) has indigenously developed 32 P nafion-based patch source (1 cm Χ 1 cm) for treating skin cancer. For t...

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Main Authors: Sridhar Sahoo, Selvam T Palani, S K Saxena, D A R Babu, A Dash
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Medical Physics
Subjects:
Online Access:http://www.jmp.org.in/article.asp?issn=0971-6203;year=2015;volume=40;issue=1;spage=13;epage=17;aulast=Sahoo
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spelling doaj-d4b7d18bd2cb4c2e823ee77f92a328772020-11-24T23:46:02ZengWolters Kluwer Medknow PublicationsJournal of Medical Physics0971-62031998-39132015-01-01401131710.4103/0971-6203.152232Monte Carlo-based dose calculation for 32 P patch source for superficial brachytherapy applicationsSridhar SahooSelvam T PalaniS K SaxenaD A R BabuA DashSkin cancer treatment involving 32 P source is an easy, less expensive method of treatment limited to small and superficial lesions of approximately 1 mm deep. Bhabha Atomic Research Centre (BARC) has indigenously developed 32 P nafion-based patch source (1 cm Χ 1 cm) for treating skin cancer. For this source, the values of dose per unit activity at different depths including dose profiles in water are calculated using the EGSnrc-based Monte Carlo code system. For an initial activity of 1 Bq distributed in 1 cm 2 surface area of the source, the calculated central axis depth dose values are 3.62 Χ 10 -10 GyBq -1 and 8.41 Χ 10 -11 GyBq -1 at 0.0125 and 1 mm depths in water, respectively. Hence, the treatment time calculated for delivering therapeutic dose of 30 Gy at 1 mm depth along the central axis of the source involving 37 MBq activity is about 2.7 hrs.http://www.jmp.org.in/article.asp?issn=0971-6203;year=2015;volume=40;issue=1;spage=13;epage=17;aulast=Sahoo32 P patch; brachytherapy; dosimetry; nafion; skin cancer
collection DOAJ
language English
format Article
sources DOAJ
author Sridhar Sahoo
Selvam T Palani
S K Saxena
D A R Babu
A Dash
spellingShingle Sridhar Sahoo
Selvam T Palani
S K Saxena
D A R Babu
A Dash
Monte Carlo-based dose calculation for 32 P patch source for superficial brachytherapy applications
Journal of Medical Physics
32 P patch; brachytherapy; dosimetry; nafion; skin cancer
author_facet Sridhar Sahoo
Selvam T Palani
S K Saxena
D A R Babu
A Dash
author_sort Sridhar Sahoo
title Monte Carlo-based dose calculation for 32 P patch source for superficial brachytherapy applications
title_short Monte Carlo-based dose calculation for 32 P patch source for superficial brachytherapy applications
title_full Monte Carlo-based dose calculation for 32 P patch source for superficial brachytherapy applications
title_fullStr Monte Carlo-based dose calculation for 32 P patch source for superficial brachytherapy applications
title_full_unstemmed Monte Carlo-based dose calculation for 32 P patch source for superficial brachytherapy applications
title_sort monte carlo-based dose calculation for 32 p patch source for superficial brachytherapy applications
publisher Wolters Kluwer Medknow Publications
series Journal of Medical Physics
issn 0971-6203
1998-3913
publishDate 2015-01-01
description Skin cancer treatment involving 32 P source is an easy, less expensive method of treatment limited to small and superficial lesions of approximately 1 mm deep. Bhabha Atomic Research Centre (BARC) has indigenously developed 32 P nafion-based patch source (1 cm Χ 1 cm) for treating skin cancer. For this source, the values of dose per unit activity at different depths including dose profiles in water are calculated using the EGSnrc-based Monte Carlo code system. For an initial activity of 1 Bq distributed in 1 cm 2 surface area of the source, the calculated central axis depth dose values are 3.62 Χ 10 -10 GyBq -1 and 8.41 Χ 10 -11 GyBq -1 at 0.0125 and 1 mm depths in water, respectively. Hence, the treatment time calculated for delivering therapeutic dose of 30 Gy at 1 mm depth along the central axis of the source involving 37 MBq activity is about 2.7 hrs.
topic 32 P patch; brachytherapy; dosimetry; nafion; skin cancer
url http://www.jmp.org.in/article.asp?issn=0971-6203;year=2015;volume=40;issue=1;spage=13;epage=17;aulast=Sahoo
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