OptGS: An R Package for Finding Near-Optimal Group-Sequential Designs

A group-sequential clinical trial design is one in which interim analyses of the data are conducted after groups of patients are recruited. After each interim analysis, the trial may stop early if the evidence so far shows the new treatment is particularly effective or ineffective. Such designs are...

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Bibliographic Details
Main Author: James Wason
Format: Article
Language:English
Published: Foundation for Open Access Statistics 2015-08-01
Series:Journal of Statistical Software
Online Access:http://www.jstatsoft.org/index.php/jss/article/view/2269