Endothelial activation by platelets from sickle cell anemia patients.

Endothelial activation by platelets from sickle cell anemia patients.

Sickle cell anemia (SCA) is associated with a hypercoagulable state. Increased platelet activation is reported in SCA and SCA platelets may present augmented adhesion to the vascular endothelium, potentially contributing to the vaso-occlusive process. We sought to observe the effects of platelets (P...

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Bibliographic Details
Main Authors: Renata Proença-Ferreira, Ana Flávia Brugnerotto, Vanessa Tonin Garrido, Venina Marcela Dominical, Daiana Morelli Vital, Marilene de Fátima Reis Ribeiro, Melissa Ercolin dos Santos, Fabíola Traina, Sara T Olalla-Saad, Fernando Ferreira Costa, Nicola Conran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3923877?pdf=render

Internet

http://europepmc.org/articles/PMC3923877?pdf=render

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