Association of promoter methylation of RASSF1A and KRAS mutations in non-small cell lung carcinoma in Kashmiri population (India)

Association of promoter methylation of RASSF1A and KRAS mutations in non-small cell lung carcinoma in Kashmiri population (India)

Background: Non-small cell lung carcinoma (NSCLC) incidence and progression is increasing because of genetic and epigenetic changes. The mutations in the Kirsten rat sarcoma (KRAS) are the most frequently oncogene aberrations in lung carcinoma patients. A candidate tumor suppressor gene (TSG) Ras As...

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Bibliographic Details
Main Authors: Naseer Ue Din Shah, Md Niamat Ali, Bashir A. Ganai, Syed Mudassar, Mosin Saleem Khan, Jasbir Kour, Ajaz Ahmad Waza, Malik Tariq Rasool, Aabid Maqbool Lone
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Heliyon
Subjects:
Cancer research
Cell biology
Adenocarcinoma
KRAS
RASSF1A
Metastasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020303339

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