Techniques for Molecular Imaging Probe Design

Techniques for Molecular Imaging Probe Design

Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly...

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Bibliographic Details
Main Authors: Fred Reynolds, Kimberly A. Kelly
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2011-11-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2011.00003
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spelling doaj-d48044eaa98a44f3b0180e4f4e1198242021-04-02T14:31:17ZengHindawi - SAGE PublishingMolecular Imaging1536-01212011-11-011010.2310/7290.2011.0000310.2310_7290.2011.00003Techniques for Molecular Imaging Probe DesignFred ReynoldsKimberly A. KellyMolecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly outpaced the number of developed molecular imaging probes. There has been a concerted effort to bridge this gap with multidisciplinary efforts in chemistry, proteomics, physics, material science, and biology—all essential to progress in molecular imaging probe development. In this review, we discuss target selection, screening techniques, and probe optimization with the aim of developing clinically relevant molecularly targeted imaging agents.https://doi.org/10.2310/7290.2011.00003
collection DOAJ
language English
format Article
sources DOAJ
author Fred Reynolds
Kimberly A. Kelly
spellingShingle Fred Reynolds
Kimberly A. Kelly
Techniques for Molecular Imaging Probe Design
Molecular Imaging
author_facet Fred Reynolds
Kimberly A. Kelly
author_sort Fred Reynolds
title Techniques for Molecular Imaging Probe Design
title_short Techniques for Molecular Imaging Probe Design
title_full Techniques for Molecular Imaging Probe Design
title_fullStr Techniques for Molecular Imaging Probe Design
title_full_unstemmed Techniques for Molecular Imaging Probe Design
title_sort techniques for molecular imaging probe design
publisher Hindawi - SAGE Publishing
series Molecular Imaging
issn 1536-0121
publishDate 2011-11-01
description Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly outpaced the number of developed molecular imaging probes. There has been a concerted effort to bridge this gap with multidisciplinary efforts in chemistry, proteomics, physics, material science, and biology—all essential to progress in molecular imaging probe development. In this review, we discuss target selection, screening techniques, and probe optimization with the aim of developing clinically relevant molecularly targeted imaging agents.
url https://doi.org/10.2310/7290.2011.00003
work_keys_str_mv AT fredreynolds techniquesformolecularimagingprobedesign
AT kimberlyakelly techniquesformolecularimagingprobedesign
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