Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis

Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis

Although there are some data concerning the nitric oxide and the cyclic 3'-5'guanosine monophosphate (cGMP) signaling pathway in trypanosomatids, there is no report about the cGMP-dependent enzymatic activity identification. In this sense, a cGMP dependent activity was detected on soluble...

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Bibliographic Details
Main Authors: LF Géigel, LL Leon
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2003-06-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Leishmania amazonensis
cyclic 3'-5'-guanosine monophosphate
metacyclogenesis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400012
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spelling doaj-d47d1c5f3afa43eb8d7eacf4e8b1ef482020-11-25T02:18:57ZengInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz.0074-02761678-80602003-06-0198449950010.1590/S0074-02762003000400012Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensisLF GéigelLL LeonAlthough there are some data concerning the nitric oxide and the cyclic 3'-5'guanosine monophosphate (cGMP) signaling pathway in trypanosomatids, there is no report about the cGMP-dependent enzymatic activity identification. In this sense, a cGMP dependent activity was detected on soluble fraction from Leishmania amazonensis promastigotes with a high metacyclic level. This information is valuable in order to explore the metabolic pathway of G kinase protein in this parasite.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400012Leishmania amazonensiscyclic 3'-5'-guanosine monophosphatemetacyclogenesis
collection DOAJ
language English
format Article
sources DOAJ
author LF Géigel
LL Leon
spellingShingle LF Géigel
LL Leon
Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis
Memórias do Instituto Oswaldo Cruz.
Leishmania amazonensis
cyclic 3'-5'-guanosine monophosphate
metacyclogenesis
author_facet LF Géigel
LL Leon
author_sort LF Géigel
title Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis
title_short Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis
title_full Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis
title_fullStr Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis
title_full_unstemmed Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis
title_sort cyclic 3'-5' guanosine monophosphate-dependent activity in leishmania amazonensis
publisher Instituto Oswaldo Cruz, Ministério da Saúde
series Memórias do Instituto Oswaldo Cruz.
issn 0074-0276
1678-8060
publishDate 2003-06-01
description Although there are some data concerning the nitric oxide and the cyclic 3'-5'guanosine monophosphate (cGMP) signaling pathway in trypanosomatids, there is no report about the cGMP-dependent enzymatic activity identification. In this sense, a cGMP dependent activity was detected on soluble fraction from Leishmania amazonensis promastigotes with a high metacyclic level. This information is valuable in order to explore the metabolic pathway of G kinase protein in this parasite.
topic Leishmania amazonensis
cyclic 3'-5'-guanosine monophosphate
metacyclogenesis
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400012
work_keys_str_mv AT lfgeigel cyclic35guanosinemonophosphatedependentactivityinleishmaniaamazonensis
AT llleon cyclic35guanosinemonophosphatedependentactivityinleishmaniaamazonensis
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