The Decrease of Uch-L1 Activity Is a Common Mechanism Responsible for Aβ 42 Accumulation in Alzheimer’s and Vascular Disease

The Decrease of Uch-L1 Activity Is a Common Mechanism Responsible for Aβ 42 Accumulation in Alzheimer’s and Vascular Disease

Alzheimer’s disease (AD) is a multifactorial pathology causing common brain spectrum disorders in affected patients. These mixed neurological disorders not only include structural AD brain changes but also cerebrovascular lesions. The main aim of the present issue is to find the factors shared by th...

Full description

Bibliographic Details
Main Authors: Michela Guglielmotto, Debora Monteleone, Valeria Vasciaveo, Ivan Enrico Repetto, Giusi Manassero, Massimo Tabaton, Elena Tamagno
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
amyloid beta
mixed dementia
Uch-L1
BACE1
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00320/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2017.00320/full

Similar Items