Positive Stability Analysis and Bio-Circuit Design for Nonlinear Biochemical Networks

This paper is concerned with positive stability analysis and bio-circuits design for nonlinear biochemical networks. A fuzzy interpolation approach is employed to approximate nonlinear biochemical networks. Based on the Lyapunov stability theory, sufficient conditions are developed to guarantee the...

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Bibliographic Details
Main Authors: Yonghui Sun, Zhinong Wei, Guoqiang Sun
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Abstract and Applied Analysis
Online Access:http://dx.doi.org/10.1155/2013/717489
Description
Summary:This paper is concerned with positive stability analysis and bio-circuits design for nonlinear biochemical networks. A fuzzy interpolation approach is employed to approximate nonlinear biochemical networks. Based on the Lyapunov stability theory, sufficient conditions are developed to guarantee the equilibrium points of nonlinear biochemical networks to be positive and asymptotically stable. In addition, a constrained bio-circuits design with positive control input is also considered. It is shown that the conditions can be formulated as a solution to a convex optimization problem, which can be easily facilitated by using the Matlab LMI control toolbox. Finally, a real biochemical network model is provided to illustrate the effectiveness and validity of the obtained results.
ISSN:1085-3375
1687-0409