The Level of TWIST1 expression determines the response of colon cancer cells to mitogen-activated protein kinases inhibitors

The Level of TWIST1 expression determines the response of colon cancer cells to mitogen-activated protein kinases inhibitors

Background/Aim: Currently, it has been proposed that combination of 5-fluorouracil (5FU) with inhibitors of the mitogen-activated protein kinases (MAPKs) signaling pathway might enhance the efficacy of 5FU-based chemotherapy in colon cancer. Our study aimed to investigate an impact of TWIST1 silenci...

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Bibliographic Details
Main Authors: Tomasz Przybyla, Martyna Wesserling, Monika Sakowicz-Burkiewicz, Izabela Maciejewska, Tadeusz Pawelczyk
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:The Saudi Journal of Gastroenterology
Subjects:
5-Fluorouracil
colon cancer
mitogen-activated protein kinases inhibitors
TWIST1
Online Access:http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2018;volume=24;issue=1;spage=37;epage=45;aulast=Przybyla

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