A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals
Using variants from the 1000 Genomes Project, RNA-seq and ChIP-seq data from related projects, this study describes a resource and survey of allele-specific binding and gene expression. A catalogue of allelic SNPs and annotation elements is available as an online resource at alleledb.gersteinlab.org...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-04-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11101 |
id |
doaj-d440bca1c75048d0a733a3fb0a6a9ba5 |
---|---|
record_format |
Article |
spelling |
doaj-d440bca1c75048d0a733a3fb0a6a9ba52021-05-11T11:11:32ZengNature Publishing GroupNature Communications2041-17232016-04-017111310.1038/ncomms11101A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individualsJieming Chen0Joel Rozowsky1Timur R. Galeev2Arif Harmanci3Robert Kitchen4Jason Bedford5Alexej Abyzov6Yong Kong7Lynne Regan8Mark Gerstein9Program in Computational Biology and Bioinformatics, Yale UniversityProgram in Computational Biology and Bioinformatics, Yale UniversityProgram in Computational Biology and Bioinformatics, Yale UniversityProgram in Computational Biology and Bioinformatics, Yale UniversityProgram in Computational Biology and Bioinformatics, Yale UniversityProgram in Computational Biology and Bioinformatics, Yale UniversityProgram in Computational Biology and Bioinformatics, Yale UniversityDepartment of Computer Science, Yale UniversityProgram in Computational Biology and Bioinformatics, Yale UniversityProgram in Computational Biology and Bioinformatics, Yale UniversityUsing variants from the 1000 Genomes Project, RNA-seq and ChIP-seq data from related projects, this study describes a resource and survey of allele-specific binding and gene expression. A catalogue of allelic SNPs and annotation elements is available as an online resource at alleledb.gersteinlab.org.https://doi.org/10.1038/ncomms11101 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jieming Chen Joel Rozowsky Timur R. Galeev Arif Harmanci Robert Kitchen Jason Bedford Alexej Abyzov Yong Kong Lynne Regan Mark Gerstein |
spellingShingle |
Jieming Chen Joel Rozowsky Timur R. Galeev Arif Harmanci Robert Kitchen Jason Bedford Alexej Abyzov Yong Kong Lynne Regan Mark Gerstein A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals Nature Communications |
author_facet |
Jieming Chen Joel Rozowsky Timur R. Galeev Arif Harmanci Robert Kitchen Jason Bedford Alexej Abyzov Yong Kong Lynne Regan Mark Gerstein |
author_sort |
Jieming Chen |
title |
A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals |
title_short |
A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals |
title_full |
A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals |
title_fullStr |
A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals |
title_full_unstemmed |
A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals |
title_sort |
uniform survey of allele-specific binding and expression over 1000-genomes-project individuals |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2016-04-01 |
description |
Using variants from the 1000 Genomes Project, RNA-seq and ChIP-seq data from related projects, this study describes a resource and survey of allele-specific binding and gene expression. A catalogue of allelic SNPs and annotation elements is available as an online resource at alleledb.gersteinlab.org. |
url |
https://doi.org/10.1038/ncomms11101 |
work_keys_str_mv |
AT jiemingchen auniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT joelrozowsky auniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT timurrgaleev auniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT arifharmanci auniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT robertkitchen auniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT jasonbedford auniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT alexejabyzov auniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT yongkong auniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT lynneregan auniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT markgerstein auniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT jiemingchen uniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT joelrozowsky uniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT timurrgaleev uniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT arifharmanci uniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT robertkitchen uniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT jasonbedford uniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT alexejabyzov uniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT yongkong uniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT lynneregan uniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals AT markgerstein uniformsurveyofallelespecificbindingandexpressionover1000genomesprojectindividuals |
_version_ |
1721446908009906176 |