Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure.

The initial step in target cell infection by human, and the closely related simian immunodeficiency viruses (HIV and SIV, respectively) occurs with the binding of trimeric envelope glycoproteins (Env), composed of heterodimers of the viral transmembrane glycoprotein (gp41) and surface glycoprotein (...

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Bibliographic Details
Main Authors: Tommi A White, Alberto Bartesaghi, Mario J Borgnia, Joel R Meyerson, M Jason V de la Cruz, Julian W Bess, Rachna Nandwani, James A Hoxie, Jeffrey D Lifson, Jacqueline L S Milne, Sriram Subramaniam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21203482/?tool=EBI