Circular RNA CHST15 Sponges miR-155-5p and miR-194-5p to Promote the Immune Escape of Lung Cancer Cells Mediated by PD-L1

Circular RNA CHST15 Sponges miR-155-5p and miR-194-5p to Promote the Immune Escape of Lung Cancer Cells Mediated by PD-L1

BackgroundThe effects of up-regulated CircCHST15 on lung cancer remained unclear. In this study, the role of CircCHST15 in lung cancer was investigated.MethodsDual-luciferase reporter verified the bioinformatics prediction that CircCHST15 targeted miR-155-5p and miR-194-5p. The correlation between C...

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Bibliographic Details
Main Authors: Jianru Yang, Yang Jia, Bing Wang, Shengrong Yang, Kun Du, Yujie Luo, Yunhe Li, Bing Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
lung cancer
CircCHST15
miR-155-5p
miR-194-5p
PD-L1
immune escape
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.595609/full

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