Robust home brew fragment sizing assay for detection of MET exon 14 skipping mutation in non–small cell lung cancer patients in resource constrained community hospitals

Robust home brew fragment sizing assay for detection of MET exon 14 skipping mutation in non–small cell lung cancer patients in resource constrained community hospitals

Background A mutation/deletion involving donor or acceptor sites for exon 14 results in splicing out of exon 14 of the mesenchymal epithelial transition (MET) gene and is known as “MET exon 14 skipping” (ΔMET14). The two recent approvals with substantial objective responses and improved progression-...

Full description

Bibliographic Details
Main Authors: Anurag Mehta, Shrinidhi Nathany, Aanchal Chopra, Sakshi Mattoo, Dushyant Kumar, Manoj Kumar Panigrahi
Format: Article
Language:English
Published: Korean Society of Pathologists & the Korean Society for Cytopathology 2021-09-01
Series:Journal of Pathology and Translational Medicine
Subjects:
met exon 14 skipping
lung neoplasms
fragment sizing assay
home brew
electrophoresis
Online Access:http://www.jpatholtm.org/upload/pdf/jptm-2021-07-15.pdf

Internet

http://www.jpatholtm.org/upload/pdf/jptm-2021-07-15.pdf

Similar Items