One Step Preparation of Peptide-Coated Gold Nanoparticles with Tunable Size

One Step Preparation of Peptide-Coated Gold Nanoparticles with Tunable Size

Gold nanoparticles (AuNPs) made from self-assembling peptides have been used in many research fields and attracted a great deal of attention due to their high stability, biocompatibility and functionality. However, existing preparation methods for peptide-coated AuNPs are post-synthesis processes, w...

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Bibliographic Details
Main Authors: Yongmei Jia, Xiaoning Yan, Xin Guo, Guohua Zhou, Peilian Liu, Zhiguo Li
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Materials
Subjects:
CALNN
peptide
gold nanoparticle
self-assembling
size
tyrosine
trypsin
Online Access:https://www.mdpi.com/1996-1944/12/13/2107
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record_format Article
spelling doaj-d4181173da8c44ef9af034d327f8a9252020-11-25T01:49:38ZengMDPI AGMaterials1996-19442019-06-011213210710.3390/ma12132107ma12132107One Step Preparation of Peptide-Coated Gold Nanoparticles with Tunable SizeYongmei Jia0Xiaoning Yan1Xin Guo2Guohua Zhou3Peilian Liu4Zhiguo Li5Key Laboratory of Clean Energy Materials Chemistry of Guangdong Higher Education Institutes, School of Chemistry and Chemical Engineering, Lingnan Normal University, Cunjin Road, Zhanjiang 524048, ChinaKey Laboratory of Clean Energy Materials Chemistry of Guangdong Higher Education Institutes, School of Chemistry and Chemical Engineering, Lingnan Normal University, Cunjin Road, Zhanjiang 524048, ChinaKey Laboratory of Clean Energy Materials Chemistry of Guangdong Higher Education Institutes, School of Chemistry and Chemical Engineering, Lingnan Normal University, Cunjin Road, Zhanjiang 524048, ChinaKey Laboratory of Clean Energy Materials Chemistry of Guangdong Higher Education Institutes, School of Chemistry and Chemical Engineering, Lingnan Normal University, Cunjin Road, Zhanjiang 524048, ChinaKey Laboratory of Clean Energy Materials Chemistry of Guangdong Higher Education Institutes, School of Chemistry and Chemical Engineering, Lingnan Normal University, Cunjin Road, Zhanjiang 524048, ChinaKey Laboratory of Clean Energy Materials Chemistry of Guangdong Higher Education Institutes, School of Chemistry and Chemical Engineering, Lingnan Normal University, Cunjin Road, Zhanjiang 524048, ChinaGold nanoparticles (AuNPs) made from self-assembling peptides have been used in many research fields and attracted a great deal of attention due to their high stability, biocompatibility and functionality. However, existing preparation methods for peptide-coated AuNPs are post-synthesis processes, which are complicated and time consuming. Therefore, a one-step preparation method for peptide-coated AuNPs is proposed here. The AuNPs obtained by this method exhibit good stability. Importantly, peptide-coated AuNPs with precise different sizes can be prepared by this method through pH control of reducing reagent tyrosine in range of 10.0~12.7. Thus, the one-step preparation method proposed here provides a significant tool for the research in different fields concerning NP size, stability and biocompatibility.https://www.mdpi.com/1996-1944/12/13/2107CALNNpeptidegold nanoparticleself-assemblingsizetyrosinetrypsin
collection DOAJ
language English
format Article
sources DOAJ
author Yongmei Jia
Xiaoning Yan
Xin Guo
Guohua Zhou
Peilian Liu
Zhiguo Li
spellingShingle Yongmei Jia
Xiaoning Yan
Xin Guo
Guohua Zhou
Peilian Liu
Zhiguo Li
One Step Preparation of Peptide-Coated Gold Nanoparticles with Tunable Size
Materials
CALNN
peptide
gold nanoparticle
self-assembling
size
tyrosine
trypsin
author_facet Yongmei Jia
Xiaoning Yan
Xin Guo
Guohua Zhou
Peilian Liu
Zhiguo Li
author_sort Yongmei Jia
title One Step Preparation of Peptide-Coated Gold Nanoparticles with Tunable Size
title_short One Step Preparation of Peptide-Coated Gold Nanoparticles with Tunable Size
title_full One Step Preparation of Peptide-Coated Gold Nanoparticles with Tunable Size
title_fullStr One Step Preparation of Peptide-Coated Gold Nanoparticles with Tunable Size
title_full_unstemmed One Step Preparation of Peptide-Coated Gold Nanoparticles with Tunable Size
title_sort one step preparation of peptide-coated gold nanoparticles with tunable size
publisher MDPI AG
series Materials
issn 1996-1944
publishDate 2019-06-01
description Gold nanoparticles (AuNPs) made from self-assembling peptides have been used in many research fields and attracted a great deal of attention due to their high stability, biocompatibility and functionality. However, existing preparation methods for peptide-coated AuNPs are post-synthesis processes, which are complicated and time consuming. Therefore, a one-step preparation method for peptide-coated AuNPs is proposed here. The AuNPs obtained by this method exhibit good stability. Importantly, peptide-coated AuNPs with precise different sizes can be prepared by this method through pH control of reducing reagent tyrosine in range of 10.0~12.7. Thus, the one-step preparation method proposed here provides a significant tool for the research in different fields concerning NP size, stability and biocompatibility.
topic CALNN
peptide
gold nanoparticle
self-assembling
size
tyrosine
trypsin
url https://www.mdpi.com/1996-1944/12/13/2107
work_keys_str_mv AT yongmeijia onesteppreparationofpeptidecoatedgoldnanoparticleswithtunablesize
AT xiaoningyan onesteppreparationofpeptidecoatedgoldnanoparticleswithtunablesize
AT xinguo onesteppreparationofpeptidecoatedgoldnanoparticleswithtunablesize
AT guohuazhou onesteppreparationofpeptidecoatedgoldnanoparticleswithtunablesize
AT peilianliu onesteppreparationofpeptidecoatedgoldnanoparticleswithtunablesize
AT zhiguoli onesteppreparationofpeptidecoatedgoldnanoparticleswithtunablesize
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