Membrane-Pore Forming Characteristics of the Bordetella pertussis CyaA-Hemolysin Domain

Membrane-Pore Forming Characteristics of the Bordetella pertussis CyaA-Hemolysin Domain

Previously, the 126-kDa Bordetella pertussis CyaA pore-forming/hemolysin (CyaA-Hly) domain was shown to retain its hemolytic activity causing lysis of susceptible erythrocytes. Here, we have succeeded in producing, at large quantity and high purity, the His-tagged CyaA-Hly domain over-expressed in...

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Bibliographic Details
Main Authors: Chattip Kurehong, Chalermpol Kanchanawarin, Busaba Powthongchin, Gerd Katzenmeier, Chanan Angsuthanasombat
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Toxins
Subjects:
CyaA-Hly
Bordetella pertussis
cooperative action
hemolytic activity
oligomeric pores
single channels
Online Access:http://www.mdpi.com/2072-6651/7/5/1486

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