Evolution of Network Biomarkers from Early to Late Stage Bladder Cancer Samples

We use a systems biology approach to construct protein-protein interaction networks (PPINs) for early and late stage bladder cancer. By comparing the networks of these two stages, we find that both networks showed very significantly different mechanisms. To obtain the differential network structures...

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Bibliographic Details
Main Authors: Yung-Hao Wong, Cheng-Wei Li, Bor-Sen Chen
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/159078