Stress Resilience of Spermatozoa and Blood Mononuclear Cells without Prion Protein

Stress Resilience of Spermatozoa and Blood Mononuclear Cells without Prion Protein

The cellular prion protein PrPC is highly expressed in neurons, but also present in non-neuronal tissues, including the testicles and spermatozoa. Most immune cells and their bone marrow precursors also express PrPC. Clearly, this protein operates in highly diverse cellular contexts. Investigations...

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Bibliographic Details
Main Authors: Malin R. Reiten, Giulia Malachin, Elisabeth Kommisrud, Gunn C. Østby, Karin E. Waterhouse, Anette K. Krogenæs, Anna Kusnierczyk, Magnar Bjørås, Clara M. O. Jalland, Liv Heidi Nekså, Susan S. Røed, Else-Berit Stenseth, Frøydis D. Myromslien, Teklu T. Zeremichael, Maren K. Bakkebø, Arild Espenes, Michael A. Tranulis
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
prion protein
stress resilience
spermatocytes
peripheral blood mononuclear cells
goat model
testes
Online Access:http://journal.frontiersin.org/article/10.3389/fmolb.2018.00001/full

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