Isolation of a Highly Purified HSC-enriched CD34+CD90+CD45RA− Cell Subset for Allogeneic Transplantation in the Nonhuman Primate Large-animal Model

Background. Allogeneic hematopoietic stem cell transplantation (allo-HCT) is a common treatment for patients suffering from different hematological disorders. Allo-HCT in combination with hematopoietic stem cell (HSC) gene therapy is considered a promising treatment option for millions of patients w...

Full description

Bibliographic Details
Main Authors: Stefan Radtke, PhD, Lucrezia Colonna, PhD, Anai M. Perez, BA, Michelle Hoffman, MS, Leslie S. Kean, MD, PhD, Hans-Peter Kiem, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2020-08-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001029