Inhibition of lipid synthesis and glucose-6-phosphate dehydrogenase in rat skin by dehydroepiandrosterone

Lipid synthesis from acetate-1-14C by rat skin was inhibited 44-56% by 2.5 × 10-4m dehydroepiandrosterone (DHA) in vitro with or without addition of glucose in the incubation medium. This inhibition affected all the lipid fractions examined (hydrocarbons, sterols, sterol esters, tri-, di- and monogl...

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Bibliographic Details
Main Authors: Vincent A. Ziboh, M.A. Dreize, S.L. Hsia
Format: Article
Language:English
Published: Elsevier 1970-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520429712

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